DR. MURALI RAMANATHAN
Dr. Murali Ramanathan
Dr. MURALI RAMANATHAN is an Associate Professor of Pharmaceutical Sciences. He joined the Department in 1994. He
received his B.Tech. (Honors) in Chemical Engineering from the Indian Institute of Technology, India in 1983. After a
four year stint in the chemical industry, he obtained his M.S. in Chemical Engineering from Iowa State University, Ames,
IA in 1987 and his Ph.D. in Bioengineering from the University of California-San Francisco and University of
California-Berkeley Joint Program in Bioengineering in 1994.
His research focus is the treatment of multiple sclerosis (MS), an inflammatory-demyelinating disease of the central
nervous system that affects over 1 million patients worldwide.
MS is a complex, variable disease that causes physical and cognitive disability: nearly 50% of patients diagnosed with
MS are unable to walk after 15 years.
The etiology and pathogenesis of MS remains poorly understood.
He is actively involved in clinical and translational multiple sclerosis research and works closely with the Baird
Multiple Sclerosis Center at the Jacobs Neurological Institute. Ongoing research includes work on the following
patient-centered MS projects:
- Molecular mechanisms of disease and treatment effects in MS and other demyelinating diseases
- Genomics of non-responsiveness and therapy optimization
- Pharmacokinetics and pharmacodynamics modeling of MS therapies
- Immunogenicity of protein drugs for MS
- Gene expression profiling and proteomics
- Mathematical models for pharmacogenomics, signal transduction processes and immunomodulatory protein networks
For a detailed description of Dr. Ramanathan's research interests CLICK HERE
Licensing Opportunities:
Is your Company still doing drug-protein binding assessments in drug development using
tedious, old fashioned technologies? You may be interested in licensing our patented invention (US Patent 6,468,757) to
measure drug-binding to serum proteins. The method is fast and inexpensive and amenable to high-throughput screening.
Contact the University at Buffalo, Office for Technology Transfer (STOR)
.
We have a novel approach for identifying druggable targets and assessing their potential efficacy and side effect
profiles. The invention will be of use and interest to those involved in drug discovery and target validation. Contact
the University at Buffalo, Office for Technology Transfer (STOR) .
Pharmaceutical Calculations:
Dr. Ramanathan has published the class notes from his Pharmacy Calculations course at the University at Buffalo as a Workbook. The Workbook has hundreds of
prescription based problems and will be very useful as a teaching tool in teaching Pharmacy Calculations.
The workbook is available for download at http://www.pharmacycalculations.org/
. Educators can request a complimentary desk copy by emailing Dr. Ramanathan (muralI@buffalo.edu).
Address:
427 Cooke
645-2842
Publications
CLICK HERE
for a list of recent publications (Limited to articles listed in the
Pub Med database).
Pharmaceutical Sciences Faculty