PHARMACOKINETIC-PHARMACODYNAMIC MODELING
Concepts and Applications

May 3-6, 1998, Buffalo, New York 14260, U.S.A.

COURSE PROGRAM

May 3 Sunday
6:00-7:00 Registration/Reception
7:00-8:00 Dr. W.J. Jusko: History & Highlights
8:00-9:30 Dinner

May 4 Monday
08:00 Continental Breakfast
08:30-09:30 Dr. J.W. Mandema: Basic Pharmacodynamic Theory
09:30-10:30 Dr. M. Danhof: Kinetics of Pharmacologic Effects
10:30-11:00 Coffee
11:00-12:30 Dr. M. Danhof: Modeling Reversible Drug Effects
12:30-01:30 Lunch
01:30-03:30 Dr. W.J. Jusko: Modeling Indirect Responses: Basic Concepts and Complexities
03:30-04:00 Break
04:00-05:30 Dr. M. Danhof: Measurement of Drug Action and Pharmacokinetic Complexities in PK/PD

May 5 Tuesday
08:00 Continental Breakfast
08:30-10:00 Dr. M. Danhof: Practical Exercises
10:00-10:30 Coffee
10:30-12:30 Dr. J.W. Mandema: Modeling Drug-Drug Interactions
12:30-01:30 Lunch
01:30-02:30 Dr. M. Danhof: Modeling Functional Adaptation
02:30-03:30 Dr. W.J. Jusko: Modeling of Irreversible Pharmacodynamic Effects
03:30-04:00 Refreshments
04:00-04:45 Dr. M. Danhof: Preclinical PK/PD in Drug Development
04:45-5:30 Dr. W.J. Jusko: Modeling Transduction Processes

May 6 Wednesday
08:00 Continental Breakfast
08:30-09:30 Dr. W.J. Jusko: Practical Exercises
09:30-10:15 Dr. W.J. Jusko: Pharmacoimmunodynamic Models
10:15-10:30 Coffee
10:30-12:00 Dr. J.W. Mandema: Population Pharmacodynamics
12:00-01:00 Lunch
01:00-01:45 Dr. H-L. Fung: Cardiovascular Pharmacodynamics
01:45-02:30 Dr. W. Krzyzanski: Modeling Circadian Rythems
02:30-02:45 Refreshments
02:45-03:45 Dr. A. Forrest: Modeling Warfarin Dynamics
03:45-04:45 Dr. J.W. Mandema: Clinical Trials Simulation
04:45-05:00 Final Discussion/Adjournment

For more information:

PK/PD MODELING
Department of Pharmaceutics, School of Pharmacy,
State University of NY at Buffalo,
519 Hochstetter Hall, Buffalo, NY 14260, U.S.A.,
phone: 716 645 2855, ext. 224; fax: 716 645 3693.
email: wjjusko@acsu.buffalo.edu


PK-PD Modeling Home Page